Drug of choice for resistant rheumatic chorea?

Drug of choice for resistant rheumatic
a) Valproate
b) Haloperidol
c) Diazepam
d) Probenecid
Correct Answer - A
Answer: - A - Valproate
Valproate, Sulpiride, & diazepam are used for symptomatic
Acute Rheumatic Fever:
Abnormal immune response to group A streptococcal infection
Commonly affecting the joints, heart, brain, and skin.
Symptoms: Arthritis, related to carditis &chorea.
Sydenham’s chorea / Chorea minor
Characterized by rapid, uncoordinated jerking movements primarily
affecting the face, hands and feet.
Signs & symptoms of chorea usually do not respond well to
treatment with antirheumatic agents
Symptomatic treatment include anticonvulsants (eg, valproate,
carbamazepine) and neuroleptics (eg, pimozide, haloperidol,
risperidone, olanzapine