Exercise Alters Breast Tumor Gene Expression :

Exercise Alters Breast Tumor Gene Expression :

A 2014 meta-analysis showed that women who engaged in the highest levels of physical activity after being diagnosed with breast cancer had a 29% lower risk for breast cancer–specific mortality and a 43% lower risk for all-cause mortality compared with inactive patients.

For the first time, a study has shown that exercise has a direct biological effect on breast tumor gene expression, providing potential insight into previously reported links between exercise and lower mortality risk in breast cancer patients who exercise relative to those who do not.

The study was published online May 23 in Clinical Cancer Research.

“We only had observational evidence that exercise has an effect on mortality risk, but [until now] we had no direct evidence that it’s exercise per se that’s helpful,” Jennifer Ligibel, MD, Dana-Farber Cancer Institute, Boston, Massachusetts.
Further larger study to follow.