Feature of microscopic polyangitis is:
a) IgG deposits in kidney
b) Bronchospasm
c) Renal involvement in 80% of cases
d) All of the above
Correct Answer - C
Answer is C (Renal involvement in 80% of cases):
Renal involvement is seen in at least 80% ofpatients with MPA.
Renal involvement is seen in at least 80% of patients with MPA
Renal involvement is seen in at least 80% of patients with MPA -
CRDT Glomerulonephritis occurs in atleast 79% of patients –
Harrison
Microscopic polyangitis is not associated with IgG Deposits in
kidney
Microscopic Polyangitis is a pauci-immune glomerulonephritis.
Immunofluorescence and electron microscopy show no immune
deposits
Microscopic Polyangitis is not associated with bronchospasm
Asthma (bronchospasm) and Eosinophilia are features of Churg-
Strauss Syndrome and are typically absent in microscopic
polyangitis.
Features H.S.
purpura Microscopic
Polyangitis
Wegner’s
Granulomatosis
Churg-
Strauss
syndrome
Deposits in
kidney
– nt (IgA
deposits) -
Bronchospasm
(Asthma)
Eosinophi
Eosinophilia - - - +
Predominant
ANCA