Fibrinopeptide A and fibrinopeptide B are acidic due to the presence of which amino acids in its structure

Fibrinopeptide A and fibrinopeptide B are
acidic due to the presence of which amino
acids in its structure -
a) Serine and threonine
b) Glutamate and aspartate
c) Histidine and lysine
d) Glutamine and valine
Correct Answer - B
Answer: B. Glutamate and aspartate
The N-terminal A and B portions of the Aα and Bβ chains are termed
fibrinopeptide A (FPA) and fibrinopeptide B (FPB), respectively.
These domains are highly negatively charged as a result of an
abundance of aspartate and glutamate residues.
The negative charges contribute to the solubility of fibrinogen in
plasma and importantly also serve to prevent aggregation by
causing electrostatic repulsion between fibrinogen molecules.