Galactomannan is a polysaccharide antigen found in the cell walls of certain fungi

Galactomannan in serum is seen in-

Galactomannan is a polysaccharide antigen found in the cell walls of certain fungi, particularly Aspergillus species. Detection of galactomannan, often through a blood test to measure its presence in serum, can be used as a diagnostic marker for invasive aspergillosis, a serious fungal infection caused by Aspergillus.

The presence of galactomannan in the serum is typically associated with invasive aspergillosis, particularly in individuals with weakened immune systems. This includes patients who are immunocompromised, such as those undergoing chemotherapy, organ transplant recipients, or individuals with HIV/AIDS.

Invasive aspergillosis can manifest as a severe and often life-threatening infection, especially if it spreads beyond the lungs to other organs. Early detection of galactomannan in the serum can aid in the timely diagnosis and treatment of invasive aspergillosis.

It’s important to note that the presence of galactomannan in the serum alone is not sufficient for a definitive diagnosis. It should be interpreted in conjunction with other clinical and diagnostic findings, such as imaging studies, culture results, and the patient’s clinical condition. Always consult a healthcare professional for a thorough evaluation and appropriate management if you suspect a fungal infection or invasive aspergillosis.