if VPL nucleus of the thalamus is involved in the stroke then there should be loss of pain perception instead of increased intensity of pain as ischemia leads to Nv damages ?
The ventroposterolateral (VPL) nucleus of the thalamus is indeed associated with the processing of sensory information, including pain signals. However, the specific effects of a stroke on pain perception can vary depending on the nature and location of the damage.
In some cases, damage to the VPL nucleus of the thalamus can result in altered or decreased pain perception. This is because the thalamus acts as a relay station for sensory information, and damage to this area can disrupt the transmission of signals related to pain.
On the other hand, strokes can also lead to complex changes in sensory processing, and in some instances, individuals may experience abnormal sensations, including increased pain sensitivity (hyperalgesia) or the perception of pain in the absence of a stimulus (allodynia). This phenomenon is thought to involve a combination of central sensitization and changes in the way the nervous system processes sensory information.
It’s essential to note that the effects of strokes on sensory perception can be highly individual, and the specific outcome can depend on various factors, including the location, extent, and nature of the damage. Additionally, different types of strokes (ischemic vs. hemorrhagic) and the structures affected can contribute to varied sensory outcomes.
If you or someone you know is experiencing changes in pain perception or other sensory symptoms following a stroke, it is crucial to seek prompt medical attention. A thorough evaluation by healthcare professionals, including neurologists, can help determine the specific impact of the stroke on sensory processing and guide appropriate management strategies.