Investigations of Pericardial effusion:
Most effusions are detected by transthoracic echocardiography which, together with ECG and assessment of markers of inflammation and myocardial injury, is essential.
CT and CMR may allow detection of loculated effusions, pericardial thickening, and masses.
In the absence of tamponade, pericardiocentesis is indicated if purulent, tuberculous, or neoplastic pericarditis is suspected.