Keshan disease in due to deficiency of

Keshan disease in due to deficiency of
a) Selenium
b) Copper
c) Zinc
d) Iron
Correct Answer - A
Ans. ‘a’ Selenium
Selenium is required for the synthesis of the amino acid
selenocysteine. Selenocysteine is present at the active site of
several human enzymes that catalyze redox reactions. Impairments
in human selenoproteins have been implicated in tumorigenesis and
atherosclerosis, and are associated with selenium deficiency
cardiomyopathy (Keshan disease)