MC malignant germ cell tumor of ovary - dysgerminoma > immature teratoma Or it’s immature teratoma which is more common?

MC malignant germ cell tumor of ovary - dysgerminoma > immature teratoma

Or it’s immature teratoma which is more common?

Among malignant germ cell tumors of the ovary, dysgerminoma is the most common type. Here’s a comparison to provide more context:

Dysgerminoma

  • Frequency: Dysgerminoma is the most common malignant germ cell tumor of the ovary, accounting for about 30-40% of all such tumors.
  • Demographics: Typically occurs in adolescents and young women.
  • Characteristics: Dysgerminomas are often unilateral and can present with abdominal pain or a palpable mass. They are sensitive to radiation and chemotherapy.
  • Prognosis: Generally has a good prognosis, especially when detected early and treated appropriately.

Immature Teratoma

  • Frequency: Immature teratomas are less common than dysgerminomas, making up about 20% of malignant germ cell tumors of the ovary.
  • Demographics: Also occurs in children and young adults.
  • Characteristics: Immature teratomas contain immature or embryonic tissues and are graded based on the amount of immature neuroepithelial tissue. They can grow rapidly and spread.
  • Prognosis: The prognosis depends on the grade of the tumor, with higher-grade tumors having a worse prognosis. However, with treatment, the outlook can be favorable.

Summary

Dysgerminoma is more common than immature teratoma among malignant germ cell tumors of the ovary. Both types of tumors typically affect younger females and require specialized treatment approaches, but dysgerminoma is more frequently encountered in clinical practice.