Neurotransmitter in mania

Neurotransmitter in mania -
a) Increased dopaine
b) Decreased dopamine
c) Increased norepinephrine
d) Decreased norepinephrine
Correct Answer - C
Ans. is ‘c’ i.e., Increased norepinephrine
Neurotransmitters in mood disorders
Most accepted biochemical hypothesis for mood disorders is the
monoamine hypothesis, according to which serotinin and
norepinephrine are the major neurotransmitters involved in mood
disorders : -

  1. Depression → Decrease in serotonin and norepinephrine. Serotonin
    is the most important neurotransmitter in depression.
  2. Mania → Increased level of norepinephrine
    Patients suffering from severe depression with suicidal
    intent/attempt appear to have a marked decrease in serotinin.
    Acetylcholine and GABA are the other neurotransmitters which are
    involved in mood disorders