Neurotransmitter in mania -
a) Increased dopaine
b) Decreased dopamine
c) Increased norepinephrine
d) Decreased norepinephrine
Correct Answer - C
Ans. is ‘c’ i.e., Increased norepinephrine
Neurotransmitters in mood disorders
Most accepted biochemical hypothesis for mood disorders is the
monoamine hypothesis, according to which serotinin and
norepinephrine are the major neurotransmitters involved in mood
disorders : -
- Depression → Decrease in serotonin and norepinephrine. Serotonin
is the most important neurotransmitter in depression. - Mania → Increased level of norepinephrine
Patients suffering from severe depression with suicidal
intent/attempt appear to have a marked decrease in serotinin.
Acetylcholine and GABA are the other neurotransmitters which are
involved in mood disorders