New glaucoma treatment with cannabigerolic acid (CBGA), a cannabis compound could ease symptoms while you sleep.
-
Eye drops developed by UBC researchers could one day treat glaucoma while you sleep – helping to heal a condition that is one of the leading causes of blindness around the world.
-
Medicated eye drops are commonly used to treat glaucoma but they’re often poorly absorbed.
-
Less than five per cent of the drug stays in the eye because most of the drops just roll off the eye.
-
Even when the drug is absorbed, it may fail to reach the back of the eye, where it can start repairing damaged neurons and relieving the pressure that characterizes glaucoma.
-
To solve these problems, the UBC team developed a hydrogel that was then filled with thousands of nanoparticles containing cannabigerolic acid (CBGA), a cannabis compound that has shown promise in relieving glaucoma symptoms.
Maryam Kabiri, Syed H. Kamal, Sandip V. Pawar, Protiva R. Roy, Maziar Derakhshandeh, Ujendra Kumar, Savvas G. Hatzikiriakos, Sazzad Hossain, Vikramaditya G. Yadav. A stimulus-responsive, in situ-forming, nanoparticle-laden hydrogel for ocular drug delivery. Drug Delivery and Translational Research, 2018; DOI: 10.1007/s13346-018-0504-x
