NK cells
Possess CD16 and CD56 markers
Mediate Antibody dependent cell mediated cytotoxicity
CD16 recognizes Fc portion of IgG Antibody bound to target cell =》release perforins and granazymes that lyse target cell
responsible against virus infected and malignant cells, parasitic infections
Tc / CD8 Cells
Class I MHC mediated cytotoxicity
TCR of Tc cell recognize Ag-MHC I complex of target cell =》release perforins and granazymes =》target cell death