Onion skin spleen is seen in
a) ITP
b) Thalassemia
c) SLE
d) Scleroderma
Correct Answer - C
Ans. is ‘c’ i.e., SLE
The characterisitc histopathologic picture of the spleen in SLE
is periaterial fibrosis or anion skin lesion.
First described by Libman and Sacks, this lesion is defined as the
presene of 3 to as many as 20 seperated layers of the normally
densely packed periarterial collagen of the penicillary or follicular
arteries producing the appearance of concentric rings (onion peel).