Oropharyngeal colostrum therapy reduces the incidence of ventilator-associated pneumonia in very low birth weight infants

NEET PG Pediatrics
#1

Oropharyngeal colostrum therapy reduces the incidence of ventilator-associated pneumonia in very low birth weight infants: a systematic review and meta-analysis

:globe_with_meridians: Ma, et al, Pediatric Research, Systematic Review 30 March 2020

:diamond_shape_with_a_dot_inside: Abstract
:diamond_shape_with_a_dot_inside: Background
Oropharyngeal colostrum (OC) is a novel feeding strategy to prevent complications of prematurity. A meta-analysis was conducted to investigate whether very low birth weight infants (VLBWs) can benefit from OC.

:diamond_shape_with_a_dot_inside: Conclusions
OC could significantly reduce the occurrence of VAP, and consequently, its routine use should be considered for VLBWs to prevent infectious diseases.

:diamond_shape_with_a_dot_inside: Impact
OC significantly reduces the occurrence of VAP and NEC in VLBW infants.
OC may reduce the incidence of VAP and NEC by increasing IgA levels.
Early OC therapy for mechanical ventilation of low-weight infants may prevent the occurrence of VAP