Pharma imp points:-

pharma imp points:-

  1. Drug protective against diabetx nephropathy? ACE inhibitors

  2. Drug which can cause cyanide toxicity ? Nitroprusside

  3. Hydralazine dec ? Afterload/preload

  4. Action of glitazone? Inc insulin sensitivity in peripheral tissue

  5. Sulfonyureas closes which channels in b-cells? K+channe l

  6. First line therapy of Type 2 DM? Metformin

  7. Which drug is teratogen ? Carbimazole/ methemazole/ propyl thiouracil

  8. Drug used in SIADH? Demeclocycline

  9. Mechanism of PPI? Irreversibly inhibit H+/K+ATPase in stomach parietal cells

  10. Carcinoid tumor is treated by? Octreoride

  11. Name antacids causes diarrhea? Magnesium hydroxide

  12. The powerful centrally acting antiemetic is? Ondansetron

  13. Metaclopromide is which receptor antagonist ? D2

  14. Myeloaupression caused by methotrexate is rescued by whih drug? Leucovori

  15. Anti Breast cancer drug having endometrial antagonist action is? Raloxifene

  16. Myelosuppresion cause by 5 florouracil is rescued by? Thymidine

  17. Hemorrhagic cystitis is side effect of ? Cyclophosphamide

  18. Nephrotoxicity caused by cisplatin is prevented by? Amifostine

  19. Name the drug which is Philadelphia chromosome tyrosine kinase inhibitor ?

Imatinib

  1. Monoclonal antibody against CD20 is ? Rituximab