Posaconazole is more effective than Voriconazole

Posaconazole is more effective than Voriconazole .Then Why Voriconazole is used and it is DOC for Invasive Aspergillosis?’

So thatvwe can use it in case voriconazole isnt effective. Best drug isnt always the doc.

Thank you sir Ranjan Kumar Patel 🙏

Sir one more doubt .

Sir azoles are hepatotoxic hence we should look for AST and ALT of patient if giving for long period of time . Sir , what period of time is considered to be long period in case of Azoles?

After several weeks like 3-4. But usually its not fatal.