Presence of an intact cell within the cytoplasm of another cell

MCQs
#1

EMPERIPOLESIS

● presence of an intact cell within the cytoplasm of another cell.
● defined by as, “the active penetration of one cell by another which remains
intact”.
● It differs from phagocytosis :- because the engulfed cell exists within another
cell and remains viable, and can exit without any physiological and morphological
changes in them.
● Etiopathogenesis of emperipolesis is uncertain.
● seen in

  1. hematolymphoid disorders e.g. myeloproliferative disorders, nonHodgkin’s
    lymphoma, idiopathic myelofibrosis, myelodysplastic syndrome (MDS)
  2. Rosai-Dorfman disease.
  3. Autoimmune hepatitis.
  4. megakaryocytic emperipolesis is seen in ---- MDS.
  5. lymphocytes within Astrocytes (emperipolesis) in multiple sclerosis plaques and brain tumors.
  6. Lymphocytic- emperipolesis----CHRONIC LYMPHOCYTIC LEUKEMIA