Previous child with NTD Folic acid dose?

Previous child with NTD Folic acid dose?

Neural tube defects (NTDs) are serious congenital malformations that occur during early fetal development when the neural tube, which forms the brain and spinal cord, fails to close properly. Folic acid supplementation has been shown to significantly reduce the risk of NTDs when taken before conception and during early pregnancy.

For women who have previously had a child with an NTD, the recommended folic acid dose to reduce the risk of recurrence may be higher than the standard dose recommended for the general population. The specific dosage may vary depending on individual factors and healthcare provider recommendations, but it is typically higher than the standard dose of 400 micrograms (mcg) per day.

In such cases, healthcare providers may recommend a higher dose of folic acid, often in the range of 4 milligrams (mg) per day (which is equivalent to 4000 mcg). This higher dosage is intended to ensure that an adequate level of folic acid is available to support neural tube closure and reduce the risk of recurrence of NTDs.

It’s important for individuals with a history of NTD-affected pregnancies to discuss their specific situation with their healthcare provider to determine the appropriate folic acid supplementation regimen. In some cases, additional prenatal testing or counseling may also be recommended to assess the risk of NTD recurrence and to provide appropriate care and support during pregnancy.