Prozone phenomenon is due to-

Prozone phenomenon is due to
a) Antigen excess
b) Antibody excess
c) False +ve reaction
d) False -ve reaction
Correct Answer - B:D
Ans. (b) and (d) Antibody excess and False-negative Ref.
Ananthanarayan 8/e, p 104, 9/ 105
Zone phenomenon (seen in agglutination and precipitation) consists
of 3 parts:

  1. Prozone = Ab excess = weak or absent precipitation reaction =
    False -ve
  2. Zone of equivalence = peak amount of precipitation.
  3. Post zone = Ag excess = weak or absent precipitation reaction.