Risk factors include family history, alcoholism, smoking, thyroid problems, liver disease, diabetes, previous hand trauma, and epilepsy.
The underlying mechanism involves the formation of abnormal connective tissue within the palmar fascia.
Initial treatment is typical with steroid injections into the affected area, occupational therapy, and physical therapy.
Among those who worsen, clostridial collagenase injections or surgery may be tried.
While radiation therapy is used to treat this condition, the evidence for this use is poor. The condition may recur despite treatment