How to approach this question ?scanty cytoplasm and no granules I can understand its lymphoblast but how to diff b/w types
Just seeing the blast to comment is terribly tugh
As given he is adolescent male and mediastinal mass is there,
Suggestive of This is Immature T cell phenotype.
Now coming to the options
A and D are of B cell neoplasm which is not in this case as Mediastinal Involvement is there and Not showing property of Mature B cell phenotype.
C won’t be the answer as this is Lymphoid progenitor Neoplasm from Image .
it were a B cell type what would have been mentioned in history ? And how to differentiate between immature n mature B cell phenotype ?
Then history might be like A children without Mediastinal involvement or any other specific information regarding B cell type in case of B-ALL
And for Mature B cell phenotype type you have to rule out symptoms of Mature B cell Neoplasm like Non Hodgkin’s B cell lymphomas
Diagnosis: T ALL
Only clue mediastinal mass and adolessent male… It’s not possible to comment by seeing the blast…
80 percent blast and mediastinal mass resembling immature T cell phenotype means T cell ALL
Presence of mediastinal mass : likely T cell ALL