Site of action of amphotericin B is:

Site of action of amphotericin B is:
a) Ribosomes
b) Cell wall
c) Plasma membrane
d) Protein
Correct Answer - B
Answer:- B - Cell wall
Polyene drug compounds like Amphotericin B acts on cell
membrane -
Amphotericin B, antifungal agent.
Chemically a polyene compound
Obtained from Streptomyces nodosus.
Polyenes have a high affinity for “ergosterol” present in the fungal
cell membrane.
Binds and gets inserted into the cell membrane forming “Micropore”.
Marked increase in permeability of cell membrane.
Polyene drug compounds like Amphotericin B acts on cell
membrane
Amphotericin B, antifungal agent.
Chemically a polyene compound
Obtained from Streptomyces nodosus.
Polyenes have a high affinity for “ergosterol” present in the fungal
cell membrane.
Binds and gets inserted into the cell membrane forming “Micropore”.
Marked increase in permeability of cell membrane