A 63-year-old smoker visits his primary care physician because of recent weight gain and worsening coughs. On physical examination the physician notes that the patient’s extremities are thinner than before, while his waist is increased in girth. The patient also has a pad of adipose tissue at the base of his neck and purple striae on his abdomen. The physician decides to run some blood tests and obtain an x-ray of the chest, which shows a central lesion. Which of the following is the most likely diagnosis?
(A) Adenocarcinoma
(B) Bronchial carcinoid
© Metastatic disease affecting the lung
(D) Small cell carcinoma
(E) Squamous cell carcinoma embolism