Sperm capacitation occurs due to
A. High cholesterol content of Acrosomal membrane
B. Decreased cholesterol content of acrosomal membrane
C. Increased calcium ions in sperm
D. Release of enzymes from flagellar membrane of sperm
The inciting factor for capacitation is cyclic AMP dependent phosphorylation with increase in intracellular pH (influx of Ca++ and efflux of H+). This leads to activation of the acrosomal membrane and promotes fusion of the membrane with the ooctye. Thus, the answer would be C. Thank you.