Sulphonamide injection causes decrease in folic acid by?

Sulphonamide injection causes decrease
in folic acid by?
a) Competitive inhibition
b) Non competitive inhibition
c) Uncompetitive inhibition
d) Allosteric inhibition
Correct Answer - A
Ans. is ‘a’ i.e., Competitive inhibition
Bacteria synthesize their own folic acid of which para aminobenzoic
acid (PABA) is a constituent - Sulfonamides, being structural
analogues of PABA, inhibit bacterial folate synthase competitively.