"Supra-acetabular osteolysis

“Supra-acetabular osteolysis can occur secondary to particular debris most commonly generated from ultra-high molecular weight polyethylene (UHMWPE) debris. Prior to the development of highly cross-linked polyethylene liners, eccentric wear or backside wear of polyethylene liners lead to the production of high volumes of polyethylene particle debris. Particulate debris led to macrophage activation and the production of osteolytic lesions behind acetabular cups or around acetabular screws. This process often occurs more than 10 years out from the index surgery and can go on to cause fracture or loosening of components due to loss of prior bone ingrowth. Osteolysis rates have significantly decreased since the introduction of highly cross-linked polyethylene liners which have much lower wear rates.”

Review more high-yield concepts about Wear & Osteolysis Basic Science on the most recent episode of The Orthobullets Podcast. Listen wherever you get your podcasts!