The bite site is better but gross oedema still present. What is the most likely cause?

A 56 year old woman with history of breast cancer 10 years ago when radical mastectomy and axillary lymph node removal were done for her now complains of swollen upper limb 3 weeks after an insect bite. The bite site is better but gross oedema still present. What is the most likely cause?

A. Lymphoedema

B. Breast Ca

C. Allergy

D. Filariasis

E. Infection