34 week primigravida punjabi khatri
comes with history of consanguineous
marriage, with history of repeated blood
transfusion to her sibling since 8
months of age. The first diagnostic test
is -
a) HPLC
b) Blood smear
c) Bone marrow
d) Hb electrophoresis
Correct Answer - B
Answer- B. Blood smear
Type of hemoglobin is detected by Hb electrophoresis.
In this case, Hb electrophoresis of the woman should be done. If she
comes positive for abnormal hemoglobin, she should be counselled
about termination of pregnancy.