The following pathogen does not satisfy “Koch’s postulates” -
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Bacillus anthracis
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Mycobacterium tuberculosis
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Clostridium tetani
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Lepra bacilli
Explanation
Koch postulates
- Robert Koch proposed a series of postulates that have been applied broadly to link many specific bacterial species with particular disease.
- Koch’s postulates are :
- The microorganism should be found in all cases of the disease in question and its distribution in the body should be in accordance with the lesions observed.
- The microorganism should be grown in pure culture in vitro (or outside the body of the host) for several generations.
- When such a pure culture is inoculated into susceptible animal species, the typical disease must result.
- The microorganism must again be isolated from the lesions of such experimentally produced disease.