The murmur depends on volume of LV

MVP as the cause of loss of coaptation of valve cusp is different so the murmur depends on volume of LV

The PR interval on an electrocardiogram (ECG) represents the time it takes for the electrical signal to travel from the atria to the ventricles of the heart. Both hypokalemia (low potassium levels) and hyperkalemia (high potassium levels) can affect the duration of the PR interval, but they have different mechanisms for causing this effect.

  1. Hypokalemia: In hypokalemia, the PR interval is prolonged due to slowed conduction of electrical signals through the heart. Low potassium levels can impair the function of cardiac cells, including the cells responsible for conducting electrical impulses. This impairment leads to a delay in the transmission of electrical signals from the atria to the ventricles, resulting in a prolonged PR interval.
  2. Hyperkalemia: In hyperkalemia, the PR interval is also prolonged, but the underlying mechanism is different. Elevated potassium levels affect the resting membrane potential of cardiac cells, making them less excitable. As a result, the conduction of electrical signals through the heart is slowed down, leading to a prolonged PR interval.

It’s important to note that other factors or conditions can also influence the duration of the PR interval. Therefore, a comprehensive evaluation by a healthcare professional is necessary to determine the precise cause of PR interval prolongation in an individual patient.