The tissue of origin of the Kaposi’s
sarcoma is ?
Correct Answer - B
Ans is ‘b’ i.e., Vascular
Kaposi sarcoma is an intermediate grade, multicentric vascular,
- The pathogenesis of kaposi sarcoma is complex, fundamentally it
is an angioproliferative disease that is not a true neoplastic sarcoma.
It is a manifestation of excessive proliferation of spindle cells that are
believed to be of vascular origin and have features in common with
endothelial and smooth muscle cells.
- Grossly-Three stages of the disease can be identified
Patch (1st stage)
Plaque (intermediate stage)
LI Nodule (last stage)
- Histologically-The changes are nonspecific in the early patch stage
and more characteristic in the nodular stage which show sheets of
plump proliferating spindle cells and endothelial in the dermis or