Treatment of clopidogrel toxicity can be done with?

Treatment of clopidogrel toxicity can be
done with ?
a) Whole human blood
b) Platelet transfusion
c) vWf transfusion
d) rFVIIa infusion
Correct Answer - D
Ans. D. rFVIIa infusion
rFVIIa (Recombinant factor Vila) has been shown to restore
thrombin generation in clopidogrel treated blood samples, and
shorten thrombin generation lag time in patients who had been
treated with aspirin and clopidogrel, and in blood samples treated
with clopidogrel’s active metabolite.
Thus they can be used for the management of clopidogrel toxicity
induced bleeding i.e. can be used to reverse the effects of
clopidogrel