Two broad categories of medications are effective in treating HPV disease:
Immune-response modifiers—these include imiquimod and interferon alfa and are primarily used in treatment of external anogenital warts or condylomata acuminata
Cytotoxic agents—these include the antiproliferative drugs podofilox, podophyllin, and 5-fluorouracil, as well as the chemodestructive or keratolytic agents salicylic acid, trichloroacetic acid, and bichloracetic acid