What are the hormonal /endocrine causes of RPL?

What are the hormonal /endocrine causes of RPL?
A multitude of endocrinological events aid in the implantation & successful growth and development of the fetus. A small number do have certain endocrine alterations that could potentially lead to RPL.

8 to 12% of all RPL are due to endocrine factors.

Common endocrine factors are :

  • Thyroid Dysfunction

  • Diabetes – Poorly controlled Type 1 Diabetes has been associated with miscarriage. Improving blood sugars before conception will improve the outcome during pregnancy.

  • Hyperprolactinemia

  • Luteal Phase Defect

  • Hyper secretion of LH (PCOS)

  • Obesity