What is the most common complication of her condition?

1-year-old African American girl is brought to the office for routine evaluation. She is learning how to walk and

says “mama” and “dada.” She recently transitioned from breast milk to cow’ s milk. Review of systems is negative.

Both parents have sickle cell trait and her sister has sickle cell disease. Her height and weight are appropriate for

her age. Physical examination shows a well-appearing, well-nourished child with no abnormalities. Laboratory

results are as follows:

Complete blood count

Hemoglobin 14 g/dl

Hematocrit 42%

Mean corpuscular volume 88 fl

Reticulocytes 2%

Hemoglobin electrophoresis

Hemoglobin A 60%

Hemoglobin S 40%

Hemoglobin F 0%

What is the most common complication of her condition?

  • O A. Acute chest syndrome
  • 0 B. Dactylitis
  • 0 C. Hematuria
  • 0 D. lschemic stroke
  • 0 E. Osteomyelitis
  • 0 F. Splenic infarction
  • 0 G. Urinary tract infection

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