1-year-old African American girl is brought to the office for routine evaluation. She is learning how to walk and
says “mama” and “dada.” She recently transitioned from breast milk to cow’ s milk. Review of systems is negative.
Both parents have sickle cell trait and her sister has sickle cell disease. Her height and weight are appropriate for
her age. Physical examination shows a well-appearing, well-nourished child with no abnormalities. Laboratory
results are as follows:
Complete blood count
Hemoglobin 14 g/dl
Hematocrit 42%
Mean corpuscular volume 88 fl
Reticulocytes 2%
Hemoglobin electrophoresis
Hemoglobin A 60%
Hemoglobin S 40%
Hemoglobin F 0%
What is the most common complication of her condition?
- O A. Acute chest syndrome
- 0 B. Dactylitis
- 0 C. Hematuria
- 0 D. lschemic stroke
- 0 E. Osteomyelitis
- 0 F. Splenic infarction
- 0 G. Urinary tract infection
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