A 59 year old man visits his physician for his yearly routine examination. He mentions that his exercise tolerance had been reduced over the last year. He also notes that he experiences shortness of breath and chest pain when he is ascending his home stairs although he lives on the second floor. He smokes 1-2 packs of cigarettes every day for 35 years. He drinks socially and uses recreational drugs occasionally. On examination, his vital signs are as follows: pulse 86/min, blood pressure 140/90 and his BMI is 30. His cardiac examination is unremarkable. He has family history of hypercholesterolemia and coronary disease. His laboratory tests show abnormal lipid profile (LDL: 230 mg/dL and HDL: 32 mg/dL).
What is the most likely vascular pathology in this patient?
A-Atherosclerosis
B-Deep venous thrombosis
C-Hyperplastic arteriosclerosis
D-Medial calcific sclerosis