What is the most sensitive investigation for detecting diabetic nephropathy?
- Creatinine clearance rate
- Urine microscopy
- Urinary albumin excretion
- Urinary protein electrophoresis
- Serum creatinine
Answer : Urinary albumin excretion
The earliest clinical evidence of diabetic nephropathy is the presence of an abnormal level of albumin in the urine. Changes in creatinine occur late.
Urinary albumin excretion