PPROM stands for preterm premature rupture of membranes, which refers to the rupture of the amniotic sac and leakage of amniotic fluid before the onset of labor in a pregnancy that is less than 37 weeks gestation.
The optimal timing for induction of labor in PPROM depends on several factors, including the gestational age of the fetus and the presence of any signs of infection.
In general, for cases of PPROM at less than 34 weeks of gestation, the decision to induce labor should be made on a case-by-case basis, weighing the risks of prematurity against the risks of intrauterine infection. In some cases, it may be necessary to delay delivery to allow for fetal lung maturity to develop with corticosteroid treatment. If delivery is indicated, it is usually recommended to wait at least 12 to 24 hours after rupture of membranes to allow time for corticosteroids to take effect.
For cases of PPROM at less than 37 weeks of gestation, the timing of delivery depends on various factors, including the gestational age of the fetus, the presence of any signs of infection, and the condition of the cervix. In general, delivery is recommended if there are signs of fetal distress, signs of infection, or if the cervix is favorable for induction. In the absence of these factors, a watchful waiting approach may be appropriate, with delivery planned for around 34 to 37 weeks of gestation.