A 36-year-old woman presents with a 4-month history of hand pain that is worse when awakening in the morning. She reports that her pain improves throughout the morning. Both hands are equally affected. Findings from a physical examination are shown in Figure. Which of the following autoantibodies is highly specific for this patient’s disorder?
- Anti-Smith antibodies
- Antihistone antibodies
- Anticentromere antibodies
- Anti-IgG antibodies
- Anti-citrullinated protein antibodies