Which of the following factors is most responsible in the formation of the DVT?

A 36-year-old woman returned from a trip 2 days ago. Yesterday she started experiencing left calf pain. The woman is afebrile with a heart rate of 82/min, a blood pressure of 129/86 mm Hg, and a respiratory rate of 14/min. On examination, the patient’s calf pain is found to intensify on dorsifl exion of the left foot. Suspecting a deep venous thrombosis (DVT), the physician performs a venous ultrasound, which confirms the diagnosis. Which of the following factors is most responsible in the formation of the DVT?

(A) Leukotriene C4
(B) Prostaglandin I2
© Renin
(D) Thromboxane A2
(E) Vascular endothelial growth factor

Ans:D