Which of the following is/ are side
effect/s of growth hormone
administration?
a) Pain at injection site
b) Glucose intolerance
c) Hypothyroidism
d) All the above
Correct Answer - D
Ans. D. All the above
[Ref KDT &hie p. 234] Adverse effects of growth hormone
Somatropin and somatrem are recombinant GH analogues.
Somatrem has an additional methionine residue and is more
immunogenic than somatropin, but allergic reactions or resistance to
treatment are not a problem.
Pain at injection site and lipodystrophy can occur.
Glucose intolerance, hypothyroidism (due to unmasking of TSH
deficiency), salt and water retention, hand stiffiress, myalgias,
headache are the possible adverse effects
Rise in intracranial tension occurs in few cases