Which of the following is true with respect to the actions of the mineralocorticoids?

Which of the following is true with respect to the actions of the mineralocorticoids?

(A) decrease carbohydrate metabolism
(B) increase appearance of the secondary sex characteristics
© increase synthesis of androgens
(D) regulate aldosterone secretion
(E) regulate sodium retention by the kidneys

Explanation

(E) The principal mineralocorticod, produced by the zona glomerulosa cells of the adrenals, is aldosterone. Synthesis of aldosterone is primarily controlled by the rennin-angiotensin system and is thus involved in control of blood pressure. Aldosterone causes sodium reabsorption by the kidneys, which in turn regulate water balance, which leads to increases in blood pressure by increasing fluid volume. Aldosterone action does not directly lead to decreased carbohydrate metabolism (choice A), is not a sex characteristic determining steroid hormone (choice B), does not result in increased synthesis of androgens (choice C), and does not regulate its own secretion (choice D).