Which one of the following blood types is associated with the greatest susceptibilty to severe cholera?

A 22-year-old man presented to hospital two days after returning from visiting his family in Bangladesh. Within a day of his return to the US, he suddenly developed profuse watery diarrhoea.
He says there had been an outbreak of diarrhoea in his family’s village in the week before his return.
Stool culture revealed a growth of Vibrio cholerae.
Which one of the following blood types is associated with the greatest susceptibilty to severe cholera?

  1. Blood Group A

  2. Blood Group AB

  3. Blood Group B

  4. Blood Group O

  5. Rhesus -ve

View Explanation

“Individuals with blood group O are more susceptible than other individuals to severe cholera, although the mechanism underlying this association is unknown.”