Which viral gene acts as carcinogen in causing carcinoma cervix -

Which viral gene acts as carcinogen in
causing carcinoma cervix -
a) P 24 - gene
b) E - gene
c) L - gene
d) H - gene
Correct Answer - B
Ans. is ‘b’ i.e., E-gene [Ref Harrison 150/e p. 1199-1200]
HPV is the most important cause of cervical cancer.
Products of E-genes (E6, E7) are related to immortalization or
malignant transformation of keratinocytes by interfering with p53 and
Rb genes, respectively