why hypokalemia with carbonic anhydrase inhibitor?
Not only CA inhibitor, loops, thiazides and CA inhibitors all send more Na to CD and this ENaC is activated and absorbs this Na causing K loss and hypokalemia.
CA inhibitors causes less Na reabsorption in the PCT. So compensatory more Na reabsorption by ENaCs in P cells in CD and loss of K+ and H+. So hypokalemia with metab alkalosis