Why is clopidogrel preferred over ticlopidine?

Why is clopidogrel preferred over
ticlopidine?
a) Lower incidence of neutropenia and thrombocytopenia
b) Lower incidence of dyslipidemia
c) Lower incidence of hyperglycemia
d) Lower incidence of postural hypotention
Correct Answer - A
Ans. A. Lower incidence of neutropenia and thrombocytopenia
[Ref KDT 6thie p. 610]
Clopidogrel:
This newer congener of ticlopidine has similar mechanism of action,
ability to inhibit platelet function and therapeutic efficacy, but
appears to be safer and better tolerated (CLASSICS study).
Clopidogrel is safer than ticlopidine as it is less associated with
hematological dyscrasias than use of ticlopidine.
A lower frequency of neutropenia, thrombocytopenia and other bone
marrow toxicity compared to ticlopidine has been recorded.
The clopidogrel as aspirin in patients at risk of ischaemic events
(CAPRIE) trial has found clopidogrel recipients to have a slightly
lower annual risk of primary ischaemic events than aspirin
recipients.