42-yr-old female
Painful strawberry gingivitis
6-week history
Also, recurrent nose bleeds and facial ulcers
Elevated c-ANCA
Positive anti–proteinase 3 antibodies (ELISA)
Normal renal function
Diagnosis
Wegener’s Granulomatosis (Polyangiitis)
Treatment
Cyclophosphamide and Prednisone
75% of treated patients achieve complete remission
90% of untreated patients die within 1 year
A high index of suspicion is required!
#oralpathology #oralmedicine #oraldiagnosis #dentistry #gingivitis #professionaldentaleclass
‘N Engl J Med 377;21’