A 15yo male has bilateral ankle edema. His BP=110/70mmHg and urinalysis shows protein++++.
What is the most likely dx?
a. HUS
b. IgA nephropathy
c. Membranous GN
d. Minimal change GN
e. Nephrotic syndrome
Q. 1. What is the key?
Q. 2. What are the points in favour of your diagnosis?
Q. What is the treatment?
Ans. 1. The key is D. Minimal change disease.
Ans. 2. Points in favour: i) Age 15 ii) Ankle oedema iii) Normotension iv) Heavy proteinuria.
Ans. 3. Treatment of choice is steroid (prednisolon). Failure of steroid or frequent relapse (>3)
cyclophosphamide.