A 36 year old woman with Rheumatoid arthritis is being started on Rituximab

A 36 year old woman with Rheumatoid arthritis is being started on Rituximab. The patient should be counseled about a small but present risk of a viral brain infection which causes damage to predominantly the white matter of the brain leading to significant neurological disability and possibly death. Which of the following viruses is implicated in this disease?

  • A. Herpes simplex virus
  • B. Varicella zoster virus
  • C. Epstein Barr virus
  • D. JC virus
  • E. Cytomegalovirus

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A 56 year old male is about to undergo a coronary angiography which may require stent placement. The interventional cardiologist decides to administer a monoclonal antibody preparation to bind GP IIb/IIIa receptor. Which of the following proteins normally binds this receptor to promote platelet function?

  • A. ADP
  • B. Interferon-gamma
  • C. Fibrinogen
  • D. Thromboxane A2
  • E. Thrombin

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