A 55-year-old woman has felt an enlarging lump in her left breast for the past year

A 55-year-old woman has felt an enlarging lump in her left breast for the past year.

A hard, irregular 5-cm mass fixed to the underlying chest wall is palpable in her left breast.
Left axillary nontender lymphadenopathy is noted.

There is no hepatosplenomegaly. A chest CT scan reveals multiple bilateral pulmonary “cannonball” nodules.

A left breast bi opsy is performed, and on microscopic examination shows high-grade infiltrating ductal carcinoma. The appearance of the nodules in her lungs

Pulmonary chemokines that bind carcinoma cell chemokine receptors